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Depression is a serious medical condition, which can lead to suicidal thoughts and behavior. A combined analysis of studies involving 9 antidepressants showed that in people under 18 this risk was 4% for those taking antidepressants compared to 2% for those taking sugar pill. This risk must be balanced with the medical need. Those starting medication should be watched closely for suicidal thoughts, worsening of depression, or unusual changes in behavior. In children and teens, Zoloft is only approved for use in those with obsessive-compulsive disorder.

Zoloft is not for everyone. People taking MAOIs or pimozide shouldn't take Zoloft. Side effects may include dry mouth, insomnia, sexual side effects, diarrhea, nausea and sleepiness. In studies, few people were bothered enough by side effects to stop taking Zoloft.

Zoloft is approved to treat depression, social anxiety disorder, posttraumatic stress disorder (PTSD), panic disorder, obsessive-compulsive disorder (OCD), and premenstrual dysphoric disorder (PMDD) in adults over age 18. It is also
approved for OCD in children and adolescents age 6-17 years.

Zoloft is not habit-forming and is not associated with weight gain. So talk to your doctor about how Zoloft might help you. Zoloft comes in 25-mg, 50-mg, and 100-mg tablets. You and your doctor can discuss a dose for you.

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